Lysosomes are relatively large organelles formed by rough endoplasmic reticulum (RER) and then packaged for the Golgi complex , containing hydrolytic enzymes and proteolytic used to digest the material of external origin (heterofagia) or internal (autophagy) that reach them. That is, are responsible for cellular digestion .
lysosomal enzymes:
The pH inside lysosomes is 4.8 (significantly lower than that of the cytosol, which neutral) because proteolytic enzymes work best at an acidic pH. Lysosome membrane stabilizes the low pH by pumping protons (H +) from the cytosol, and also protects the cytosol and the rest of the cell of digestive enzymes that are inside the lysosome.
lysosomal enzymes capable of digesting bacteria and other substances that enter the cell by phagocytosis, endocytosis or other processes.
Lysosomes use their enzymes to recycle the different cell organelles, and are classified, digesting them and releasing their components into the cytosol. In this way the cell organelles are continually replenished. The digestion of organelles called autophagy. For example, liver cells were completely reconstituted every two weeks.
most important enzymes of the lysosome are
Lipase, which digests lipids,
glucosidase, which digests carbohydrates,
Proteases, which digest proteins,
Nucleases, which digest nucleic acids.
only present in animal cells.
lysosomal enzymes capable of digesting bacteria and other substances that enter the cell by phagocytosis, endocytosis or other processes.
Lysosomes use their enzymes to recycle the different cell organelles, and are classified, digesting them and releasing their components into the cytosol. In this way the cell organelles are continually replenished. The digestion of organelles called autophagy. For example, liver cells were completely reconstituted every two weeks.
most important enzymes of the lysosome are
Lipase, which digests lipids,
glucosidase, which digests carbohydrates,
Proteases, which digest proteins,
Nucleases, which digest nucleic acids.
only present in animal cells.
Lysosomal Diseases:
are diseases caused by dysfunction of a lysosomal enzyme or the release of these enzymes incrontrolada in the cytosol, resulting in the Cell lysis.
In some cases the release of enzymes plays a physiological role, allowing reabsorption of structures that are no longer useful, for example the tail of tadpoles during metamorphosis.
0 comments:
Post a Comment